Event Dime

Stigmasterol from Pluchea indica Leaves Reduces Spermatogenesis and Alters Sperm Morphology in Male Rat: In Vivo and In Silico Study [version 1; peer review: 3 approved with reservations]

Arts & Culture
When:
May 14, 2026 ยท 1:13 PM
Source:
F1000Research

Background Limited male contraception choices have prompted the hunt for natural antifertility drugs. This experimental study investigates the antifertility effects of stigmasterol extracted from Pluchea indica leaves in male rats (Rattus norvegicus). Methods This was a randomized experimental study involving twenty-four male rats, which were randomly allocated into four groups (n = 6/group): one control group and three treatment groups receiving stigmasterol at 0.25, 0.5, and 0.75 mg/kg body we

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