Event Dime

Bioinformatics-based Investigation to Unveiling The miRNA-Immunity Axis in The Tumor Microenvironment of Pancreatic Cancer [version 3; peer review: 1 approved with reservations, 1 not approved]

Arts & Culture
When:
May 22, 2026 ยท 4:20 PM
Source:
F1000Research

Background In this Bioinformatics study, we took in account the cell types variation of tumor microenvironment (TME) in Pancreatic Ductal Adenocarcinoma (PDAC), with a particular attention to miRNAs dysregulated pathways influencing immune responses, and especially memory CD4+ T cells. Methods For cell types and differentially expressed genes in memory CD4+ T cells, scRNA-seq was conducted on PDAC and non-tumoral pancreas samples. Putative miRNA targeting sequences on downregulated genes were in

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