Event Dime

Factors Associated with Kidney Stone Occurrence: A Path Analysis of Genetic Polymorphism CaSR, CLDN14, VDR, ALPL, Clinical Factors, and Demographical Characteristics [version 1; peer review: awaiting peer review]

Arts & Culture
When:
June 1, 2026 ยท 4:44 AM
Source:
F1000Research

Background Kidney stone disease is a common global urological problem influenced by inflammatory, clinical, demographic, and genetic factors, with genetics estimated to account for up to 50% of susceptibility. However, few studies have comprehensively evaluated genetic polymorphisms alongside clinical and demographic determinants, and the underlying mechanisms linking these risk factors to stone formation remain insufficiently understood. This study aimed to clarify how these factors contribute

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